The agreement was officially cancelled by the Allies at the San Remo Conference in April 1920, when the mandate of Palestine was entrusted to Great Britain. The Sykes-Picot agreement was only part of the secret war diplomacy concerning the Middle East. It was supplemented by agreements with two other war powers interested in the region, Russia and Italy, as well as a series of subsequent British actions and commitments, such as the Balfour Declaration and correspondence with the Hashemite family. Despite these and other changes, the term “Sykes-Picot” also refers to the general settlement of peace in the Middle East and the political order it has established. I also have the honour of declaring that Her Majesty`s Government is proposing to the Russian Government to fully enter into the agreement in order to exchange notes that correspond to those exchanged by this Government and its Government of Excellence on April 26 last year. Copies of these notes will be communicated to Excellence as soon as they are exchanged. I would also like to remind Your Excellency that the conclusion of this agreement for practical consideration raises the question of whether Italy is participating in a partition or reorganization of Turkey in Asia, as formulated in Article 9 of the agreement of 26 April 1915 between Italy and its allies. After the outbreak of war in the summer of 1914, the Allies – Britain, France and Russia – had much discussion about the future of the Ottoman Empire, which is now fighting on the side of Germany and the central powers, and its vast area in the Middle East, Arabia and southern Europe. In March 1915, Britain signed a secret agreement with Russia, whose plans for the territory of the Empire had prompted the Turks to join Germany and Austria-Hungary in 1914.
Under its terms, Russia would annex the Ottoman capital, Constantinople, and retain control of the Dardanelles (the extremely important strait that connects the Black Sea to the Mediterranean) and the Gallipoli Peninsula, the target of a major Allied military invasion, which began in April 1915.